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Indian Harvard Student Develops Potential Non-Invasive Cancer Diagnosis Procedure

Indian Harvard Student Develops Potential Non-Invasive Cancer Diagnosis Procedure

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Indian American Harvard student Neil Davey, has developed a blood-testing device that pushes the possibility of non-invasive cancer diagnosis one step closer to reality. His technique involves injecting a tiny amount of blood into a microfluidic device to encapsulate single cells from the blood stream in individual microfluidic drops. Once the cells have been encapsulated, Davey uses a PCR to target and amplify fragments of cancer DNA within the drops. By linking DNA amplification to a fluorescent output, he can shine a laser onto the drops to detect and quantify brightness, which would indicate the presence of cancer DNA in a circulating tumor cell. This technology is extremely sensitive and has the potential to detect as few as one cancer cell from a billion normal cells in the blood.

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